Program for the 5th Dutch Stem Cell Meeting 13th April 2012
Auditorium, Sanquin Amsterdam

Registration (exhibition room) 8.30 – 9.30
Opening
09.30 – 09.40
Gerald de Haan
Hematopoiesis
Chair: Carlijn Voermans
09.40 –10.00 Emma de Pater
(EUR)
The timing of GATA2 function in hematopoiesis.
10.00 – 10.20 Sabrina Zeddies
(Sanquin)
The transcription factor MEIS1 regulates early erythroid and megakaryocytic cell fate by upregulation of GATA1.
10.20 – 10.40

Karin Klauke
(UMCG)

Polycomb Cbx orthologs mediate the switch between hematopoietic stem cell self-renewal and differentiation.

10.40 – 11.00

Claudia Brandao
(Sanquin)

Central memory CD8 T cells regulate hematopoietic stem cell function.

Coffee break (exhibition room) 11.00 – 11.40
Stem cells and their environment
Chair: Elaine Dzierzak
11.40 – 12.00

Koen Schepers
(UMCU)

Myeloproliferative neoplasms cause expansion of osteoblastic bone marrow niche cells that promote disease maintenance.

12.00 – 12.20

Monika Bialecka
(Hubrecht)

Cdx2 is crucial for maintenance and proper differentiation of small intestinal stem cells.

12.20 – 12.40

Sabine Middendorp
(UMCU)

The fate of adult mouse intestinal stem cells is intrinsically programmed and determines location-specific intestinal function.

12.40 – 13.00

Martti Maimets
(UMCG)

Towards characterizing mouse salivary gland stem cells.

Lunch (exhibition room)13.00 – 14.00
14.00 – 14.20 Cindy Loomans
(Hubrechts)
Generation of human pancreatic organoids in a three dimensional culture system as a new source for beta cells.

Pluripotent stem cells
Chair: Gerald de Haan

14.20 – 14.40 Dorota Kurek
(EMC)

Endogenous Wnt proteins induce spontaneous mesendoderm-like differentiation in epiblast and hESCs.

14.40 – 15.00 Yaser Atlasi
(EMC)
Wnt signaling regulates lineage priming in mouse embryonic stem cells through Tcf3 down-regulation.
15.00 – 15.20

Matthew Birket
(LUMC)

An important role for a mitochondrial regulator in determining hESC-derived cardiomyocyte identity.

Tea break (exhibition room)15.20 – 15.40
15.40 – 16.00 Cheryl Dambrot
(LUMC)
Human induced pluripotent stem cells as in vitro model for hypertrophic cardiomyopathy.
16.00 – 16.20 Valeria Orlova
(LUMC)
Endothelial cells from human pluripotent stem cells (hPSCs) as a model system to study vascular diseases.
Plenary lecture
Chair: Martijn Nolte
16.20 – 17.10 Hiro Nakauchi
University of Tokyo, Japan
iPS technology and its future therapeutic potentials
Closing 17.10 Martijn Nolte
Drinks (Foyer) 17.15 – 18.15